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ea0075p13 | Pituitary and neuroendocrinology | EYES2021

Consecutive adrenal cushing´s syndrome and cushing´s disease in a patient with somatic CTNNB1, USP8, and NR3c1 mutations

Detomas Mario , Altieri Barbara , Schlotelburg Wiebke , Appenzeller Silke , Schlaffer Sven , Coras Roland , Schirbel Andreas , Wild Vanessa , Kroiss Matthias , Sbiera Silviu , Fassnacht Martin , Deutschbein Timo

Context: The occurrence of different subtypes of endogenous Cushings syndrome (CS) in single individuals is extremely rare. We here present the case of a female patient who was successfully cured from adrenal CS 4 years before being diagnosed with Cushing's disease (CD).Case Description: A 50-year-old female was diagnosed with ACTH-independent CS and a left-sided adrenal adenoma in January 2015. After adrenalectomy and histopathological co...

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Endocrine Abstracts

Consecutive adrenal cushing´s syndrome and cushing´s disease in a patient with somatic CTNNB1, USP8, and NR3c1 mutations

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